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Get to Know Your Gut Heroes: Short Chain Fatty Acids

There is a lot going on inside our gut every second of every day; the microbiome is hard at work, keeping us healthy and running smoothly. The gut is a fascinating environment with many interconnected systems and pathways that are in charge of almost everything!  

Today we’re taking a closer look at Short Chain Fatty Acids (SCFAs) and the role they play in gut health. SCFAs are tiny powerhouses that play a vital role in maintaining a happy gut and can even help prevent chronic diseases.
Whaaaat? YES! 

What Are Short Chain Fatty Acids?

Imagine a bustling community within your gut, where trillions of friendly bacteria live and work. These beneficial bacteria feast on fiber, particularly soluble prebiotic fiber. During this feast, they produce SCFAs as a byproduct. 

Yes, SCFAs are our good gut bug’s poop. There, we said it! **giggles coming from the back of class** Now let’s get serious again! 

SCFAs produce a variety of beneficial compounds that work wonders for your gut health. Let's break down the primary SCFAs and the remarkable ways they impact your digestive system: 


Acetate is like the rockstar of SCFAs, as it's the most abundant one produced in your gut. This superstar compound plays a vital role in energy metabolism. 

It serves as a valuable energy source for your gut cells, helping to nourish and maintain the health of the cells that line your digestive tract. By supporting the growth and repair of these cells, acetate promotes a strong gut lining and nutrient absorption. 


Propionate steps into the spotlight with its unique benefits for gut health. This SCFA not only provides energy to your gut cells but also has the superpower to regulate appetite and control blood sugar levels. 

By influencing the release of hunger and fullness hormones, propionate helps you feel satisfied after a meal and assists in maintaining stable blood sugar levels. This can be particularly beneficial for weight management and the prevention of conditions like type 2 diabetes.


Ah, butyrate, the multitasking SCFA that truly deserves a standing ovation! **Take a bow, Butyrate!** This SCFA compound is known for its incredible impact on gut health. 

It plays a significant role in nourishing the cells of your colon, known as colonocytes. These cells rely on butyrate as their primary energy source, promoting their growth and supporting a healthy colon. 

Additionally, butyrate has anti-inflammatory properties, helping to reduce inflammation in the gut and potentially preventing conditions such as inflammatory bowel disease (IBD). 

It also supports the balance of the gut microbiome, keeping the harmful bacteria in check and allowing the beneficial ones to thrive, set up shop, and multiply! WooHoo! Party time! 

The combined effects of acetate, propionate, and butyrate create an all-star cast in your gut, promoting a healthy environment for digestion and overall well-being.

So, how can you make the most of these gut-loving compounds? We will get to that but, first, let’s talk about what happens when you have low levels of short-chain fatty acids. 

Low levels of short-chain fatty acids (SCFAs), can have several implications for your health; here are the top five: 

Impaired Gut Health: SCFAs play a vital role in maintaining a healthy gut. When SCFAs are lacking, the balance of the gut microbiome can be disrupted, allowing harmful bacteria to thrive. This imbalance can lead to digestive issues, such as bloating, constipation, and diarrhea. Additionally, a weakened gut lining due to low SCFAs may compromise nutrient absorption and contribute to inflammation. 

Increased Inflammation: SCFAs have anti-inflammatory properties that help keep inflammation in check. When SCFA levels are low, the body's ability to control inflammation is compromised. Chronic inflammation can contribute to a range of health problems, including autoimmune conditions, cardiovascular disease, and metabolic disorders. 

Weakened Immune Function: SCFAs play a crucial role in supporting a healthy immune system. They help regulate immune responses and promote the growth of beneficial bacteria that help your immune system send out the troops when there is an invasion! 

When SCFAs are scarce, immune function is slowed, increasing the risk of infections, allergies, and other immune-related disorders.

Increased Risk of Chronic Diseases: Low SCFA levels have been associated with an increased risk of various chronic diseases. For example, decreased SCFA production has been linked to a higher likelihood of developing conditions such as inflammatory bowel disease (IBD), type 2 diabetes, obesity, and cardiovascular diseases. 

Weight Management Challenges: SCFAs are involved in regulating appetite and promoting feelings of fullness. When SCFA levels are low, it can disrupt the signaling mechanisms that control hunger and satiety. This imbalance contributes to increased cravings for sugary and fatty foods, overeating, and challenges in maintaining a healthy weight. 

Mental Health Impact: When it comes to mental health, the role of short-chain fatty acids should not be underestimated. Low levels of SCFAs can have significant implications on your well-being, affecting your mood and emotional response. 

When SCFA levels are low, this delicate balance can be disrupted, potentially increasing the risk of depression and anxiety. How? SCFAs have been linked to the production of serotonin, a neurotransmitter known for its mood-regulating properties. Insufficient SCFAs may result in decreased serotonin levels, impacting your overall emotional well-being. (More on this in a future post; stay tuned!) 

NOTE:  It's important to acknowledge that mental health is complex and influenced by many factors. Low SCFA levels alone may not be the sole cause of mental health challenges, but they can certainly play a significant role in their development or exacerbation. Please reach out to your healthcare team! 

So what can you do to create an all-star cast in YOUR gut and make the most of SCFAs?

One effective way is to incorporate more fiber into your meal plan! Aim for 30 grams of fiber daily!

Soluble fiber serves as the fuel for SCFA production in your gut. By providing the right nourishment for your gut bacteria, soluble fiber helps ensure a steady supply of SCFAs, enabling them to carry out their mission and create a bustling environment that keeps you healthy and strong! 

If you want to boost the production of those amazing short-chain fatty acids in your gut, it's time to bring some superhero foods to the table. These fiber-rich delights provide the nourishment your gut bacteria need to produce SCFAs. So, let's unveil the top food champions that can help unleash the power of SCFAs:

Fruits and Vegetables:

Load up on nature's bounty and eat more plants! Fruits and vegetables, especially those with edible skins and seeds, are packed with fiber. Think apples, berries, oranges, broccoli, carrots, and leafy greens. These fiber-filled wonders provide the fuel for SCFA production, supporting a healthy gut environment.

Whole Grains:

Swap refined grains for their whole-grain counterparts. Whole grains like oats, quinoa, brown rice, and whole wheat are abundant in fiber. They provide a sustained release of energy, keeping your gut bacteria happily producing SCFAs all day long! 


Lentils, chickpeas, beans, and peas are not only delicious but also rich in fiber. They serve as fantastic sources of prebiotics, the nourishment that fuels SCFA production. Add them to soups and salads, or create flavorful bean-based dishes to give your gut bacteria a fiber feast. YUM!

Nuts and Seeds:

These tiny fiber powerhouses have a big fiber punch! Almonds, walnuts, chia seeds, ground flaxseeds, and sunflower seeds are high in both soluble and insoluble fiber. Sprinkle them on your morning oatmeal or toss them into smoothies and salads for an added fiber boost.

Prebiotic Supplements:

To supercharge your SCFA production, consider a prebiotic supplement like just better.® fiber. Our single-ingredient, all-natural, Non-GMO prebiotic fiber sets the stage for round-the-clock SCFA production! 

Who should try prebiotic supplements? 

A supplement is a good idea for anyone who finds it challenging to eat 30 grams of fiber every day —which is most of us! In fact, 97% of Americans are fiber deficient. That means very few of us consume enough fiber to produce the SCFAs our bodies need to thrive.  

Want to fix that? 

just better.® fiber is a simple solution for busy people looking for ways to improve gut health and manage a healthy weight! And because just better.® is 100% dissolvable and flavorless, you can add it to anything! 

Remember, variety is key! Aim for a colorful plate that includes a diverse range of fruits, vegetables, whole grains, legumes, nuts, and seeds. By embracing a fiber-rich lifestyle, you will be actively nourishing your gut bacteria, ensuring they have the fuel they need to produce those valuable SCFAs that protect our health! 

So, let the fiber feast begin, and let your gut superheroes thrive! Remember, a happy, healthy gut leads to a happier, healthier you! 


Live… just better.®!